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Tbio
ETV2
ETS translocation variant 2

Protein Summary
Description
Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000379026
  • ENSP00000368312
  • ENSG00000105672
  • ENST00000402764
  • ENSP00000384524
  • ENST00000403402
  • ENSP00000385369

Symbol
  • ER71
  • ETSRP71
  • ER71
  • ETSRP71
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.76
molecular function
0.76
biological process
0.75
cell type or tissue
0.72
tissue sample
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.73   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 153   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.73   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 153   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (15)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Sequence Model (ISM)
NTNU_SB
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (50)
1 – 10 of 50
FOXC2
Tbio
Family: TF
Novelty: 0.00438844
Score: 0.771
Data Source: STRINGDB
GATA2
Tbio
Family: TF
Novelty: 0.00153967
Score: 0.753
Data Source: STRINGDB
KDR
Tclin
Family: Kinase
Novelty: 0.00016219
Score: 0.749
Data Source: STRINGDB
TEK
Tclin
Family: Kinase
Novelty: 0.00079268
Score: 0.712
Data Source: STRINGDB
VEGFA
Tclin
Novelty: 0.0000378
Score: 0.681
Data Source: STRINGDB
FOXC1
Tbio
Family: TF
Novelty: 0.00387011
Score: 0.667
Data Source: STRINGDB
TAL1
Tbio
Family: TF
Novelty: 0.00294416
Score: 0.666
Data Source: STRINGDB
MMP1
Tchem
Family: Enzyme
Novelty: 0.00030922
Score: 0.621
Data Source: STRINGDB
LMO2
Tbio
Novelty: 0.0038279
Score: 0.602
Data Source: STRINGDB
CDH5
Tbio
Novelty: 0.00072649
Score: 0.59
Data Source: STRINGDB
Publication Statistics
PubMed Score  71.73

PubMed score by year
PubTator Score  24.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer