F2RL2
Proteinase-activated receptor 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.84 | ||
molecular function | 0.73 | ||
virus perturbation | 0.64 | ||
microRNA | 0.63 | ||
hub protein | 0.58 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
Reactome | G alpha (q) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | GPCR ligand binding | ||||
Reactome | Hemostasis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Class A/1 (Rhodopsin-like receptors) | ||||
G alpha (q) signalling events | ||||
GPCR downstream signalling | ||||
GPCR ligand binding | ||||
Hemostasis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 3 | 7 | 10 | 99.7 | |||||
platelet count | 2 | 3 | 4 | 97.8 | |||||
reticulocyte count | 3 | 3 | 7 | 95.7 | |||||
reticulocyte measurement | 2 | 3 | 6 | 94.7 | |||||
proteinase-activated receptor 1 measurement | 1 | 1 | 1 | 80.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 10 | 99.7 | |||||
platelet count | 4 | 97.8 | |||||
reticulocyte count | 7 | 95.7 | |||||
reticulocyte measurement | 6 | 94.7 | |||||
proteinase-activated receptor 1 measurement | 1 | 80.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | coagulation factor II thrombin receptor like 2 | VGNC:6870 | 100614246 | |||||
Macaque | coagulation factor II thrombin receptor like 2 | 707260 | ||||||
Mouse | MGI:1298208 | 14064 | ||||||
Rat | RGD:620871 | 29636 | ||||||
Dog | coagulation factor II thrombin receptor like 2 | VGNC:53169 | 607963 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | coagulation factor II thrombin receptor like 2 | |||||
Macaque | coagulation factor II thrombin receptor like 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | coagulation factor II thrombin receptor like 2 | |||||
PMID | Year | Title |
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