You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
NYNRIN
Protein NYNRIN

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382554
  • ENSP00000371994
  • ENSG00000205978

Symbol
  • CGIN1
  • KIAA1305
  • CGIN1
  • KIAA1305
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.83
cell type or tissue
0.56
cell line
0.53
microRNA
0.5
virus perturbation
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.02   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 12   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.02   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 12   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
CDH8
Tbio
Novelty:  0.04055999
p_int:  0.999999862
p_ni:  1.38e-7
Score:  0.235
Data Source:  BioPlex,STRINGDB
CRYAA
Tchem
Novelty:  0.01914081
p_int:  0.99999982
p_ni:  4.9e-8
p_wrong:  1.31e-7
Data Source:  BioPlex
FAM167A
Tbio
Novelty:  0.05232679
p_int:  0.999999635
p_ni:  3.62e-7
p_wrong:  2e-9
Score:  0.173
Data Source:  BioPlex,STRINGDB
CRYAB
Tchem
Novelty:  0.00464213
p_int:  0.999998978
p_ni:  0.000001022
Score:  0.273
Data Source:  BioPlex,STRINGDB
SDR39U1
Tdark
Family:  Enzyme
Novelty:  0.38626113
Score:  0.746
Data Source:  STRINGDB
ZBED8
Tdark
Novelty:  2.26997341
Score:  0.711
Data Source:  STRINGDB
STOML1
Tbio
Novelty:  0.05746576
Score:  0.684
Data Source:  STRINGDB
STXBP6
Tbio
Novelty:  0.13195671
Score:  0.671
Data Source:  STRINGDB
KRBA2
Tdark
Novelty:  1.26888218
Score:  0.67
Data Source:  STRINGDB
ZBTB11
Tdark
Family:  TF
Novelty:  0.45418638
Score:  0.655
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (21)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
7
3
12
94.9
sex hormone-binding globulin measurement
6
1
6
87.5
alkaline phosphatase measurement
1
1
0
11.2
79.5
apolipoprotein B measurement
1
1
1
75.7
testosterone measurement
3
1
3
75
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
12
94.9
sex hormone-binding globulin measurement
6
87.5
alkaline phosphatase measurement
0
11.2
79.5
apolipoprotein B measurement
1
75.7
testosterone measurement
3
75
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
NYN domain and retroviral integrase containing
VGNC:3349
452822
Mouse
MGI:2652872
277154
Rat
RGD:6486974
100912447
Dog
NYN domain and retroviral integrase containing
VGNC:44083
490625
Horse
NYN domain and retroviral integrase containing
VGNC:20994
100054117
Species
Name
OMA
EggNOG
Inparanoid
Chimp
NYN domain and retroviral integrase containing
Mouse
Rat
Dog
NYN domain and retroviral integrase containing
Horse
NYN domain and retroviral integrase containing
Publication Statistics
PubMed Score 8.02
PubMed score by year
PubTator Score 4.00
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title