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Tdark
NXPE4
NXPE family member 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375478
  • ENSP00000364627
  • ENSG00000137634
  • ENST00000424261
  • ENSP00000401503

Symbol
  • C11orf33
  • FAM55D
  • FAM55D
  • C11orf33
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.67
PubMedID
0.47
trait
0.46
protein complex
0.4
cellular component
0.39


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.48   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 77   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.48   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (15)
NXPH2
Tdark
Novelty:  0.65790631
Score:  0.623
Data Source:  STRINGDB
NXPH1
Tbio
Novelty:  0.10081993
Score:  0.623
Data Source:  STRINGDB
NXPH4
Tbio
Novelty:  0.09172552
Score:  0.622
Data Source:  STRINGDB
NXPE1
Tdark
Novelty:  1.36399926
Score:  0.562
Data Source:  STRINGDB
NXPH3
Tdark
Novelty:  0.405045
Score:  0.556
Data Source:  STRINGDB
ADGRL1
Tbio
Family:  GPCR
Novelty:  0.00957739
Score:  0.548
Data Source:  STRINGDB
FAM3D
Tbio
Novelty:  0.11834339
Score:  0.481
Data Source:  STRINGDB
VSIG2
Tbio
Novelty:  0.32398032
Score:  0.471
Data Source:  STRINGDB
PRKACA
Tchem
Family:  Kinase
Novelty:  0.03869658
Score:  0.445
Data Source:  STRINGDB
CHST5
Tbio
Family:  Enzyme
Novelty:  0.10903299
Score:  0.44
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
2
0
1.1
90.8
blood protein measurement
1
1
1
27.4
1
1
0
1.1
8.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
90.8
blood protein measurement
1
27.4
0
1.1
8.3
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
neurexophilin and PC-esterase domain family member 4
VGNC:12661
740659
Macaque
neurexophilin and PC-esterase domain family member 4
695749
Mouse
MGI:1924792
244853
Dog
neurexophilin and PC-esterase domain family member 4
VGNC:44076
489394
Horse
neurexophilin and PC-esterase domain family member 4
VGNC:20989
100070876
Species
Name
OMA
EggNOG
Inparanoid
Chimp
neurexophilin and PC-esterase domain family member 4
Macaque
neurexophilin and PC-esterase domain family member 4
Mouse
Dog
neurexophilin and PC-esterase domain family member 4
Horse
neurexophilin and PC-esterase domain family member 4
Publication Statistics
PubMed Score 1.48
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
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PMID
Year
Title