Protein Summary
This gene encodes a member of the neurexophilin family of neuropeptide-like glycoproteins. The encoded protein contains a variable N-terminal domain, a highly conserved neurexophilin and PC-esterase (NXPE) central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein binds alpha neurexins, a group of presynaptic transmembrane receptors that promote adhesion between dendrites and axons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
- ENST00000273347
- ENSP00000273347
- ENSG00000144815
- ENST00000477909
- ENSP00000418369
- ENST00000491511
- ENSP00000417485
- FAM55C
- FAM55C
- MST115
- MSTP115
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
co-expressed gene | 0.98 | ||
transcription factor perturbation | 0.88 | ||
kinase perturbation | 0.84 | ||
histone modification site profile | 0.72 | ||
microRNA | 0.69 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.66 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 38 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.66 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 38 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0