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Tdark
NXPE2
NXPE family member 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000389586
  • ENSP00000374237
  • ENSG00000204361

Symbol
  • FAM55B
  • FAM55B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.67
gene perturbation
0.62
tissue
0.61
cell line
0.48
cellular component
0.31


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.72   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 12   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.72   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 12   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (14)
FRMPD3
Tdark
Novelty:  4.19248406
Score:  0.589
Data Source:  STRINGDB
TMEM132E
Tdark
Novelty:  0.27039617
Score:  0.588
Data Source:  STRINGDB
ASB11
Tdark
Novelty:  0.84862254
Score:  0.577
Data Source:  STRINGDB
IGSF9B
Tdark
Novelty:  0.23454299
Score:  0.546
Data Source:  STRINGDB
LHFPL1
Tdark
Novelty:  0.6561829
Score:  0.54
Data Source:  STRINGDB
MROH2B
Tdark
Novelty:  0.06107976
Score:  0.53
Data Source:  STRINGDB
DMGDH
Tbio
Family:  Enzyme
Novelty:  0.03936436
Score:  0.434
Data Source:  STRINGDB
CDH16
Tbio
Novelty:  0.03884426
Score:  0.426
Data Source:  STRINGDB
NXPH2
Tdark
Novelty:  0.65790631
Score:  0.416
Data Source:  STRINGDB
NXPH1
Tbio
Novelty:  0.10081993
Score:  0.416
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
4
2
8
95.9
3
2
0
1.1
90.8
body mass index
3
1
3
86.6
educational attainment
1
4
4
81.4
body weight
1
1
1
43.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
8
95.9
0
1.1
90.8
body mass index
3
86.6
educational attainment
4
81.4
body weight
1
43.2
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
neurexophilin and PC-esterase domain family member 2
VGNC:6700
740719
Mouse
MGI:1925502
78252
Rat
RGD:2323193
100363350
Species
Name
OMA
EggNOG
Inparanoid
Chimp
neurexophilin and PC-esterase domain family member 2
Mouse
Rat
Publication Statistics
PubMed Score 0.72
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title