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Tbio
NUFIP2
Nuclear fragile X mental retardation-interacting protein 2

Protein Summary
Description
Binds RNA.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000225388
  • ENSP00000225388
  • ENSG00000108256
  • ENST00000579665
  • ENSP00000463450

Symbol
  • KIAA1321
  • PIG1
  • 82-FIP
  • FIP-82
  • 182-FIP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.99
transcription factor perturbation
0.96
transcription factor binding site profile
0.93
virus perturbation
0.92
microRNA
0.83


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.23   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 78   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.23   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (87)
G3BP2
Tbio
Family:  Enzyme
Novelty:  0.04786241
p_int:  0.999982888
p_ni:  0.000017112
Score:  0.827
Data Source:  BioPlex,STRINGDB
ATXN2L
Tbio
Novelty:  0.01996982
p_int:  0.999954885
p_ni:  0.000045115
Score:  0.904
Data Source:  BioPlex,STRINGDB
LSM12
Tbio
Novelty:  0.0593959
p_int:  0.995241895
p_ni:  0.004758105
Score:  0.591
Data Source:  BioPlex,STRINGDB
DDX6
Tbio
Family:  Enzyme
Novelty:  0.01032357
p_int:  0.993308522
p_ni:  0.006691478
Score:  0.795
Data Source:  BioPlex,STRINGDB
G3BP1
Tbio
Family:  Enzyme
Novelty:  0.00589987
p_int:  0.982003126
p_ni:  0.017996874
Score:  0.849
Data Source:  BioPlex,STRINGDB
ATXN2
Tbio
Novelty:  0.00373116
p_int:  0.958751644
p_ni:  0.041248356
Score:  0.458
Data Source:  BioPlex,STRINGDB
RELA
Tchem
Family:  TF
Novelty:  0.0007137
p_int:  0.948716992
p_ni:  0.051172321
p_wrong:  0.000110687
Score:  0.226
Data Source:  BioPlex,STRINGDB
VWCE
Tbio
Novelty:  0.09328341
p_int:  0.915783395
p_ni:  0.084216605
Data Source:  BioPlex
TRIM11
Tbio
Family:  Enzyme
Novelty:  0.02243955
p_int:  0.849922152
p_ni:  0.150077847
p_wrong:  1e-9
Data Source:  BioPlex
THSD4
Tbio
Novelty:  0.12898073
p_int:  0.805990481
p_ni:  0.194009519
Score:  0.185
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HGNC
Disease Associations (null)
No disease associations found
GWAS Traits (31)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
5
4
5
99.4
platelet count
2
2
2
78.1
educational attainment
1
2
2
67.7
heel bone mineral density
2
2
2
65.1
smoking behaviour measurement
1
1
1
59.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
5
99.4
platelet count
2
78.1
educational attainment
2
67.7
heel bone mineral density
2
65.1
smoking behaviour measurement
1
59.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
NUFIP2, FMR1 interacting protein 2
VGNC:10326
454546
Macaque
NUFIP2, FMR1 interacting protein 2
711330
Mouse
MGI:1915814
68564
Rat
RGD:1596719
681371
Dog
NUFIP2, FMR1 interacting protein 2
VGNC:44040
480631
Species
Name
OMA
EggNOG
Inparanoid
Chimp
NUFIP2, FMR1 interacting protein 2
Macaque
NUFIP2, FMR1 interacting protein 2
Mouse
Rat
Dog
NUFIP2, FMR1 interacting protein 2
Publication Statistics
PubMed Score 10.23
PubMed score by year
PubTator Score 80.87
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title