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Tbio
NTN3
Netrin-3

Protein Summary
Description
Netrins control guidance of CNS commissural axons and peripheral motor axons.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000293973
  • ENSP00000293973
  • ENSG00000162068

Symbol
  • NTN2L
  • NTN2L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
protein domain
0.73
transcription factor
0.59
cell line
0.52
gene perturbation
0.49


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.05   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.05   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
NEO1
Tbio
Novelty:  0.00625858
Score:  0.98
Data Source:  Reactome,STRINGDB
CDON
Tbio
Novelty:  0.00447262
Score:  0.9
Data Source:  Reactome,STRINGDB
UNC5A
Tbio
Novelty:  0.03749855
Score:  0.715
Data Source:  STRINGDB
UNC5B
Tbio
Novelty:  0.01474065
Score:  0.697
Data Source:  STRINGDB
UNC5C
Tbio
Novelty:  0.02045906
Score:  0.639
Data Source:  STRINGDB
UNC5D
Tbio
Novelty:  0.06891857
Score:  0.612
Data Source:  STRINGDB
TPPP2
Tdark
Novelty:  0.22245887
Score:  0.605
Data Source:  STRINGDB
IQSEC3
Tbio
Novelty:  0.23174323
Score:  0.548
Data Source:  STRINGDB
KBTBD12
Tdark
Novelty:  3.42794501
Score:  0.534
Data Source:  STRINGDB
KLHDC8B
Tbio
Novelty:  0.15409379
Score:  0.532
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
Developmental Biology (R-HSA-1266738)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Developmental Biology
Reactome
Myogenesis
Name
Explore in Pharos
Explore in Source
Developmental Biology
Myogenesis
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
2
2
2
55.8
mean reticulocyte volume
1
1
1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
2
55.8
mean reticulocyte volume
1
35
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
netrin 3
VGNC:5853
467873
Mouse
MGI:2443456
224617
Rat
RGD:619811
114524
Dog
netrin 3
VGNC:44008
479878
Horse
netrin 3
VGNC:51204
100147434
Species
Name
OMA
EggNOG
Inparanoid
Chimp
netrin 3
Mouse
Rat
Dog
netrin 3
Horse
netrin 3
Publication Statistics
PubMed Score 9.05
PubMed score by year
PubTator Score 4.26
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title