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Tbio
NRSN2
Neurensin-2

Protein Summary
Description
May play a role in maintenance and/or transport of vesicles.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382285
  • ENSP00000371722
  • ENSG00000125841
  • ENST00000382291
  • ENSP00000371728
  • ENST00000621012
  • ENSP00000482706

Symbol
  • C20orf98
  • C20orf98
  • dJ1103G7.6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.62
small molecule perturbation
0.59
cell type or tissue
0.54
histone modification site profile
0.53
cellular component
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.72   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 164   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.72   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
CD1B
Tbio
Novelty:  0.00102701
p_int:  0.999773873
p_ni:  0.000183493
p_wrong:  0.000042634
Score:  0.179
Data Source:  BioPlex,STRINGDB
FAM234B
Tdark
Novelty:  1.53957047
p_int:  0.999643654
p_ni:  0.000165682
p_wrong:  0.000190664
Score:  0.186
Data Source:  BioPlex,STRINGDB
FITM2
Tdark
Novelty:  0.01882177
p_int:  0.854995215
p_ni:  0.125395719
p_wrong:  0.019609066
Score:  0.161
Data Source:  BioPlex,STRINGDB
MANSC1
Tdark
Novelty:  0.91681036
p_int:  0.805439615
p_ni:  0.002520866
p_wrong:  0.192039519
Data Source:  BioPlex
ZDHHC17
Tbio
Family:  Enzyme
Novelty:  0.03288707
p_int:  0.757418258
p_ni:  0.242581718
p_wrong:  2.4e-8
Score:  0.214
Data Source:  BioPlex,STRINGDB
ZBBX
Tdark
Novelty:  1.66474399
Score:  0.732
Data Source:  STRINGDB
WDR49
Tdark
Novelty:  1.46160123
Score:  0.667
Data Source:  STRINGDB
ARMCX2
Tbio
Novelty:  0.09904258
Score:  0.651
Data Source:  STRINGDB
NECAP2
Tdark
Novelty:  0.4141034
Score:  0.636
Data Source:  STRINGDB
FSTL5
Tbio
Novelty:  0.09979909
Score:  0.627
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (7)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
LIFEdb
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
1
1
1
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
1
49.5
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
neurensin 2
VGNC:14269
458438
Macaque
neurensin 2
714586
Mouse
MGI:2684969
228777
Rat
RGD:1586322
689978
Dog
neurensin 2
VGNC:43977
609687
Species
Name
OMA
EggNOG
Inparanoid
Chimp
neurensin 2
Macaque
neurensin 2
Mouse
Rat
Dog
neurensin 2
Publication Statistics
PubMed Score 9.72
PubMed score by year
PubTator Score 3.25
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title