Tdark NRN1L Neuritin-like protein

Protein Summary

Description

The protein encoded by this gene is extracellular and enhances both neurite growth and neuronal survival. The encoded protein is found both as a GPI anchored membrane-bound form and as a secreted form. This activity-related ligand functions as a homodimer or heterodimer. [provided by RefSeq, Feb 2017]

Uniprot Accession IDs

• Q496H8
• Q6UWH7

Gene Name

• NRN1L

Ensembl ID

• ENST00000339176
• ENSP00000342411
• ENSG00000188038

Symbol

• UNQ2446
• cpg15-2
• MRCC2446

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.48
transcription factor	0.46
cell line	0.44
tissue	0.44
cell type or tissue	0.4

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.34   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 91   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.34   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0