You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
NRM
Nurim

Protein Summary
Description
The protein encoded by this gene contains transmembrane domains and resides within the inner nuclear membrane, where it is tightly associated with the nucleus. This protein shares homology with isoprenylcysteine carboxymethyltransferase enzymes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000259953
  • ENSP00000259953
  • ENSG00000137404
  • ENST00000376420
  • ENSP00000365602
  • ENST00000376421
  • ENSP00000365603
  • ENST00000383570
  • ENSP00000373064
  • ENSG00000206484
  • ENST00000383571
  • ENSP00000373065
  • ENST00000422181
  • ENSP00000409285
  • ENSG00000234809
  • ENST00000422664
  • ENSP00000394788
  • ENSG00000228854
  • ENST00000422747
  • ENSP00000414927
  • ENSG00000236843
  • ENST00000427944
  • ENSP00000405789
  • ENST00000431322
  • ENSP00000398752
  • ENSG00000228867
  • ENST00000438502
  • ENSP00000397755
  • ENSG00000235773
  • ENST00000445058
  • ENSP00000389958
  • ENST00000449041
  • ENSP00000399560
  • ENST00000450138
  • ENSP00000407111
  • ENST00000456720
  • ENSP00000392502
  • ENST00000610775
  • ENSP00000481407
  • ENST00000612190
  • ENSP00000482593
  • ENST00000613827
  • ENSP00000481406
  • ENST00000617159
  • ENSP00000478812
  • ENST00000617220
  • ENSP00000483875
  • ENST00000620249
  • ENSP00000482740

Symbol
  • NRM29
  • NRM29
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.68
cellular component
0.62
transcription factor binding site profile
0.58
transcription factor perturbation
0.54
small molecule perturbation
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 96.26   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 51   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 96.26   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 51   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
ATP2B2
Tbio
Family:  Transporter
Novelty:  0.007782
p_int:  0.999997426
p_ni:  0.000002041
p_wrong:  5.32e-7
Data Source:  BioPlex
TNFSF18
Tbio
Novelty:  0.01423949
p_int:  0.999995204
p_ni:  0.000004707
p_wrong:  8.9e-8
Data Source:  BioPlex
TSPAN31
Tbio
Novelty:  0.13580467
p_int:  0.999988868
p_ni:  0.000008754
p_wrong:  0.000002378
Data Source:  BioPlex
CRNN
Tbio
Novelty:  0.01648731
p_int:  0.984974612
p_ni:  0.015025357
p_wrong:  3.1e-8
Score:  0.187
Data Source:  BioPlex,STRINGDB
HS3ST2
Tbio
Family:  Enzyme
Novelty:  0.0611326
p_int:  0.954920755
p_ni:  0.000034182
p_wrong:  0.045045063
Score:  0.219
Data Source:  BioPlex,STRINGDB
ZG16B
Tbio
Novelty:  0.08792924
p_int:  0.80365285
p_ni:  0.196347139
p_wrong:  1.1e-8
Score:  0.167
Data Source:  BioPlex,STRINGDB
CNGB1
Tbio
Family:  IC
Novelty:  0.01034916
Score:  0.799
Data Source:  STRINGDB
LBR
Tbio
Family:  Epigenetic
Novelty:  0.00205961
Score:  0.738
Data Source:  STRINGDB
CNGB3
Tchem
Family:  IC
Novelty:  0.01174942
Score:  0.734
Data Source:  STRINGDB
SUN2
Tbio
Novelty:  0.01387591
Score:  0.724
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (144)
Items per page:
1 – 5 of 144
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
2
0
1.1
92.5
2
2
0
1.1
92.5
2
2
0
1.1
92.5
2
2
0
1.1
92.5
2
2
0
1.1
92.5
Items per page:
1 – 5 of 144
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
92.5
0
1.1
92.5
0
1.1
92.5
0
1.1
92.5
0
1.1
92.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
nurim
VGNC:48899
471957
Macaque
nurim
713998
Mouse
MGI:2146855
106582
Rat
RGD:1302966
361791
Horse
nurim
VGNC:50488
100055517
Species
Name
OMA
EggNOG
Inparanoid
Chimp
nurim
Macaque
nurim
Mouse
Rat
Horse
nurim
Publication Statistics
PubMed Score 96.26
PubMed score by year
PubTator Score 6.50
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title