NPRL2
GATOR complex protein NPRL2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.71 | ||
transcription factor binding site profile | 0.69 | ||
histone modification site profile | 0.56 | ||
tissue sample | 0.55 | ||
molecular function | 0.53 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
KEGG | mTOR signaling pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
mTOR signaling pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 5 | 11 | 99.2 | |||||
reticulocyte count | 2 | 4 | 8 | 98.7 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 85.1 | |||||
chronotype measurement | 1 | 1 | 0 | 1 | 66.8 | ||||
macrophage inflammatory protein 1b measurement | 1 | 2 | 2 | 66.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte measurement | 11 | 99.2 | |||||
reticulocyte count | 8 | 98.7 | |||||
mean reticulocyte volume | 1 | 85.1 | |||||
chronotype measurement | 0 | 1 | 66.8 | ||||
macrophage inflammatory protein 1b measurement | 2 | 66.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | NPR2 like, GATOR1 complex subunit | 460393 | ||||||
Macaque | NPR2 like, GATOR1 complex subunit | 701924 | ||||||
Mouse | MGI:1914482 | 56032 | ||||||
Rat | RGD:1308927 | 363138 | ||||||
Dog | NPR2 like, GATOR1 complex subunit | VGNC:43930 | 476614 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | NPR2 like, GATOR1 complex subunit | |||||
Macaque | NPR2 like, GATOR1 complex subunit | |||||
Mouse | ||||||
Rat | ||||||
Dog | NPR2 like, GATOR1 complex subunit | |||||
PMID | Year | Title |
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