NOTCH4
Neurogenic locus notch homolog protein 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
trait | 1 | ||
cellular component | 0.91 | ||
PubMedID | 0.87 | ||
disease | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Defective LFNG causes SCDO3 | ||||
Reactome | Disease | ||||
Reactome | Diseases associated with O-glycosylation of proteins | ||||
Reactome | Diseases of glycosylation | ||||
Reactome | Gene expression (Transcription) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Defective LFNG causes SCDO3 | ||||
Disease | ||||
Diseases associated with O-glycosylation of proteins | ||||
Diseases of glycosylation | ||||
Gene expression (Transcription) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
complement C4 measurement | 2 | 4 | 7 | 97.4 | ||||||
complement C4 measurement | 2 | 4 | 7 | 97.4 | ||||||
complement C4 measurement | 2 | 4 | 7 | 97.4 | ||||||
complement C4 measurement | 2 | 4 | 7 | 97.4 | ||||||
1 | 3 | 0 | 2.6 | 96.9 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
complement C4 measurement | 7 | 97.4 | |||||
complement C4 measurement | 7 | 97.4 | |||||
complement C4 measurement | 7 | 97.4 | |||||
complement C4 measurement | 7 | 97.4 | |||||
0 | 2.6 | 96.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:107471 | 18132 | ||||||
Rat | RGD:1303282 | 406162 | ||||||
Dog | notch 4 | VGNC:43900 | 481726 | |||||
Horse | notch 4 | VGNC:20819 | 100059541 | |||||
Cow | notch 4 | VGNC:32179 | 536128 | |||||
PMID | Year | Title |
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