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Tchem
NMUR2
Neuromedin-U receptor 2

Protein Summary
Description
Receptor for the neuromedin-U and neuromedin-S neuropeptides. This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000255262
  • ENSP00000255262
  • ENSG00000132911

Symbol
  • NMU2R
  • TGR1
  • FM4
  • FM-4
  • TGR1
  • NMU2R
  • TGR-1
  • NMU-R2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
1
biological process
0.77
gene perturbation
0.71
protein domain
0.58
microRNA
0.53


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 114.29   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 177   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 114.29   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 177   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 22
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 71
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0