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Tdark
NKG7
Protein NKG7

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000221978
  • ENSP00000221978
  • ENSG00000105374

Symbol
  • GIG1
  • GIG1
  • GMP-17
  • p15-TIA-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.76
gene perturbation
0.7
tissue sample
0.66
PubMedID
0.46
transcription factor
0.43


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.79   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.79   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (53)
GNLY
Tbio
Novelty:  0.00183877
Score:  0.883
Data Source:  STRINGDB
GZMB
Tchem
Family:  Enzyme
Novelty:  0.00052869
Score:  0.88
Data Source:  STRINGDB
GZMH
Tbio
Family:  Enzyme
Novelty:  0.01480634
Score:  0.877
Data Source:  STRINGDB
PRF1
Tchem
Novelty:  0.0002835
Score:  0.875
Data Source:  STRINGDB
GZMA
Tbio
Family:  Enzyme
Novelty:  0.00322362
Score:  0.861
Data Source:  STRINGDB
GZMK
Tbio
Family:  Enzyme
Novelty:  0.01355915
Score:  0.715
Data Source:  STRINGDB
CST7
Tbio
Novelty:  0.03651959
Score:  0.711
Data Source:  STRINGDB
TYROBP
Tbio
Family:  Enzyme
Novelty:  0.00410031
Score:  0.699
Data Source:  STRINGDB
CCL5
Tchem
Novelty:  0.00032607
Score:  0.648
Data Source:  STRINGDB
CD2
Tclin
Novelty:  0.00037283
Score:  0.648
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
2
2
61.8
neutrophil count
2
2
2
58.2
HbA1c measurement
1
1
1
44.2
lymphocyte percentage of leukocytes
1
1
1
33.1
body height
1
1
1
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
61.8
neutrophil count
2
58.2
HbA1c measurement
1
44.2
lymphocyte percentage of leukocytes
1
33.1
body height
1
17.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
natural killer cell granule protein 7
VGNC:11210
456245
Macaque
natural killer cell granule protein 7
719624
Mouse
MGI:1931250
72310
Rat
RGD:621523
171062
Horse
natural killer cell granule protein 7
VGNC:20749
100062828
Species
Name
OMA
EggNOG
Inparanoid
Chimp
natural killer cell granule protein 7
Macaque
natural killer cell granule protein 7
Mouse
Rat
Horse
natural killer cell granule protein 7
Publication Statistics
PubMed Score 16.79
PubMed score by year
PubTator Score 13.01
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title