NHLRC1
E3 ubiquitin-protein ligase NHLRC1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.83 | ||
protein domain | 0.73 | ||
transcription factor binding site profile | 0.65 | ||
biological process | 0.64 | ||
tissue sample | 0.59 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Disease | ||||
Reactome | Diseases of carbohydrate metabolism | ||||
Reactome | Diseases of metabolism | ||||
Reactome | Glycogen metabolism | ||||
Reactome | Glycogen storage diseases | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Disease | ||||
Diseases of carbohydrate metabolism | ||||
Diseases of metabolism | ||||
Glycogen metabolism | ||||
Glycogen storage diseases | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
response to mercaptopurine | 1 | 1 | 0 | 7.7 | 85.5 | ||||
thiopurine methyltransferase activity measurement | 1 | 1 | 0 | 7.7 | 85.5 | ||||
2 | 1 | 0 | 1.1 | 77 | |||||
1 | 1 | 0 | 5.6 | 21.5 | |||||
age at onset | 1 | 1 | 0 | 5.6 | 21.5 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
response to mercaptopurine | 0 | 7.7 | 85.5 | ||||
thiopurine methyltransferase activity measurement | 0 | 7.7 | 85.5 | ||||
0 | 1.1 | 77 | |||||
0 | 5.6 | 21.5 | |||||
age at onset | 0 | 5.6 | 21.5 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | NHL repeat containing E3 ubiquitin protein ligase 1 | VGNC:3589 | 747581 | |||||
Macaque | NHL repeat containing E3 ubiquitin protein ligase 1 | 704451 | ||||||
Mouse | MGI:2145264 | 105193 | ||||||
Rat | RGD:735081 | 364682 | ||||||
Dog | NHL repeat containing E3 ubiquitin protein ligase 1 | VGNC:43800 | 474161 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | NHL repeat containing E3 ubiquitin protein ligase 1 | |||||
Macaque | NHL repeat containing E3 ubiquitin protein ligase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | NHL repeat containing E3 ubiquitin protein ligase 1 | |||||
PMID | Year | Title |
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