NFIB
Nuclear factor 1 B-type
Protein Summary
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
- ENST00000380953
- ENSP00000370340
- ENSG00000147862
- ENST00000380959
- ENSP00000370346
- ENST00000543693
- ENSP00000442888
- CTF
- MACID
- NF1-B
- NFI-B
- NFIB2
- NFIB3
- NF-I/B
- NFI-RED
- HMGIC/NFIB
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
PubMedID | 1 | ||
transcription factor perturbation | 1 | ||
disease perturbation | 0.97 | ||
virus perturbation | 0.88 | ||
trait | 0.86 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 235.77 (req: < 5)
Gene RIFs: 72 (req: <= 3)
Antibodies: 191 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 235.77 (req: >= 5)
Gene RIFs: 72 (req: > 3)
Antibodies: 191 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 25
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0