Tbio NEUROG1 Neurogenin-1

Protein Summary

Description

Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).

Uniprot Accession IDs

• Q92886
• Q5U0Q9
• Q96HE1
• NGN-1

Gene Name

• NEUROG1

Ensembl ID

• ENST00000314744
• ENSP00000317580
• ENSG00000181965

Symbol

• BHLHA6
• NEUROD3
• NGN
• NGN1
• AKA
• ngn1
• Math4C
• bHLHa6
• NEUROD3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.79
PubMedID	0.68
molecular function	0.63
transcription factor binding site profile	0.58
cell type or tissue	0.53

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Basic Helix-loop-helix Transcription Factor / Neurogenin-1

Protein / Nucleic Acid Binding / Nuclease / Neurogenin-1

DTO Classes

Protein / Enzyme / Nuclease / Neurogenin-1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 213.16   (req: < 5)

Gene RIFs: 13   (req: <= 3)

Antibodies: 535   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 213.16   (req: >= 5)

Gene RIFs: 13   (req: > 3)

Antibodies: 535   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 33

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0