NEDD4L
E3 ubiquitin-protein ligase NEDD4-like
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
transcription factor perturbation | 0.98 | ||
transcription factor binding site profile | 0.92 | ||
virus perturbation | 0.92 | ||
transcription factor | 0.91 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Antigen processing: Ubiquitination & Proteasome degradation | ||||
Reactome | Budding and maturation of HIV virion | ||||
Reactome | Class I MHC mediated antigen processing & presentation | ||||
Reactome | Disease | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Antigen processing: Ubiquitination & Proteasome degradation | ||||
Budding and maturation of HIV virion | ||||
Class I MHC mediated antigen processing & presentation | ||||
Disease | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 4 | 7 | 7 | 3.6 | 99.4 | ||||
serum alanine aminotransferase measurement | 2 | 3 | 2 | 13 | 93.8 | ||||
alkaline phosphatase measurement | 2 | 4 | 3 | 9.2 | 93.6 | ||||
mathematical ability | 4 | 3 | 4 | 89.8 | |||||
aspartate aminotransferase measurement | 2 | 2 | 1 | 7.8 | 80.2 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum gamma-glutamyl transferase measurement | 7 | 3.6 | 99.4 | ||||
serum alanine aminotransferase measurement | 2 | 13 | 93.8 | ||||
alkaline phosphatase measurement | 3 | 9.2 | 93.6 | ||||
mathematical ability | 4 | 89.8 | |||||
aspartate aminotransferase measurement | 1 | 7.8 | 80.2 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 455443 | ||||||
Macaque | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 700282 | ||||||
Mouse | MGI:1933754 | 83814 | ||||||
Rat | RGD:735047 | 291553 | ||||||
Dog | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | VGNC:43721 | 476189 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | |||||
Macaque | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | |||||
Mouse | ||||||
Rat | ||||||
Dog | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | |||||
PMID | Year | Title |
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