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Tclin
NDUFAB1
Acyl carrier protein, mitochondrial

Protein Summary
Description
Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (PubMed:27626371).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000007516
  • ENSP00000007516
  • ENSG00000004779
  • ENST00000570319
  • ENSP00000458770

Symbol
  • ACP
  • ACP1
  • SDAP
  • FASN2A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.99
kinase perturbation
0.97
transcription factor perturbation
0.94
virus perturbation
0.9
molecular function
0.81


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 555.26   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 555.26   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 1