NCOA3
Nuclear receptor coactivator 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 1 | ||
protein domain | 1 | ||
kinase | 0.98 | ||
transcription factor binding site profile | 0.96 | ||
molecular function | 0.94 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of HOX genes during differentiation | ||||
Reactome | Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Reactome | Developmental Biology | ||||
Reactome | ESR-mediated signaling | ||||
Reactome | Estrogen-dependent gene expression | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of HOX genes during differentiation | ||||
Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Developmental Biology | ||||
ESR-mediated signaling | ||||
Estrogen-dependent gene expression | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | CAFA | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 3 | 5 | 6 | 94 | |||||
apolipoprotein A 1 measurement | 2 | 5 | 5 | 93.4 | |||||
balding measurement | 1 | 1 | 1 | 49.5 | |||||
snoring measurement | 1 | 1 | 0 | 1 | 24.5 | ||||
1 | 1 | 0 | 1.3 | 7.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 6 | 94 | |||||
apolipoprotein A 1 measurement | 5 | 93.4 | |||||
balding measurement | 1 | 49.5 | |||||
snoring measurement | 0 | 1 | 24.5 | ||||
0 | 1.3 | 7.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | nuclear receptor coactivator 3 | VGNC:6203 | 458308 | |||||
Macaque | nuclear receptor coactivator 3 | 705431 | ||||||
Mouse | MGI:1276535 | 17979 | ||||||
Rat | RGD:620109 | 84584 | ||||||
Dog | nuclear receptor coactivator 3 | VGNC:54658 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | nuclear receptor coactivator 3 | |||||
Macaque | nuclear receptor coactivator 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | nuclear receptor coactivator 3 | |||||
PMID | Year | Title |
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