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Tbio
NCAM1
Neural cell adhesion molecule 1

Protein Summary
Description
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000316851
  • ENSP00000318472
  • ENSG00000149294
  • ENST00000529356
  • ENSP00000482205
  • ENST00000531044
  • ENSP00000484943
  • ENST00000621128
  • ENSP00000481083
  • ENST00000621850
  • ENSP00000480774

Symbol
  • NCAM
  • CD56
  • NCAM
  • MSK39
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.98
transcription factor perturbation
0.91
trait
0.86
protein domain
0.85
cellular component
0.79


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5324.25   (req: < 5)
Gene RIFs: 263   (req: <= 3)
Antibodies: 3031   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5324.25   (req: >= 5)
Gene RIFs: 263   (req: > 3)
Antibodies: 3031   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0