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Tbio
NAPG
Gamma-soluble NSF attachment protein

Protein Summary
Description
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. This gene encodes soluble NSF attachment protein gamma. The soluble NSF attachment proteins (SNAPs) enable N-ethyl-maleimide-sensitive fusion protein (NSF) to bind to target membranes. NSF and SNAPs appear to be general components of the intracellular membrane fusion apparatus, and their action at specific sites of fusion must be controlled by SNAP receptors particular to the membranes being fused. The product of this gene mediates platelet exocytosis and controls the membrane fusion events of this process.[provided by RefSeq, Dec 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322897
  • ENSP00000324628
  • ENSG00000134265

Symbol
  • SNAPG
  • GAMMASNAP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.96
virus perturbation
0.96
transcription factor perturbation
0.88
cellular component
0.82
gene perturbation
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 49.22   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 172   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 49.22   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 172   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (189)
VAMP4
Tbio
Novelty:  0.02949854
p_int:  0.999999999
p_ni:  1e-9
Score:  0.98
Data Source:  BioPlex,STRINGDB
STX7
Tbio
Novelty:  0.03109969
p_int:  0.999999996
p_ni:  4e-9
Score:  0.889
Data Source:  BioPlex,STRINGDB
VTI1B
Tbio
Novelty:  0.00955467
p_int:  0.999999837
p_ni:  1.63e-7
Score:  0.863
Data Source:  BioPlex,STRINGDB
STX12
Tbio
Novelty:  0.03836262
p_int:  0.999999768
p_ni:  2.32e-7
Score:  0.858
Data Source:  BioPlex,STRINGDB
VAMP5
Tbio
Novelty:  0.09958312
p_int:  0.999897318
p_ni:  0.000102678
p_wrong:  3e-9
Score:  0.641
Data Source:  BioPlex,STRINGDB
STX8
Tbio
Novelty:  0.01083752
p_int:  0.999877887
p_ni:  0.000122113
Score:  0.943
Data Source:  BioPlex,STRINGDB
PRKAR1B
Tbio
Family:  Enzyme
Novelty:  0.05355517
p_int:  0.999145942
p_ni:  0.000854038
p_wrong:  2e-8
Score:  0.437
Data Source:  BioPlex,STRINGDB
THRSP
Tbio
Novelty:  0.00938864
p_int:  0.999035471
p_ni:  0.000964528
Data Source:  BioPlex
PIPOX
Tbio
Family:  Enzyme
Novelty:  0.04107707
p_int:  0.998580032
p_ni:  0.001419874
p_wrong:  9.4e-8
Score:  0.163
Data Source:  BioPlex,STRINGDB
STXBP6
Tbio
Novelty:  0.13195671
p_int:  0.998563973
p_ni:  0.001410239
p_wrong:  0.000025789
Score:  0.823
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (14)
Asparagine N-linked glycosylation (R-HSA-446203)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 14
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Asparagine N-linked glycosylation
Reactome
COPI-dependent Golgi-to-ER retrograde traffic
Reactome
COPI-mediated anterograde transport
Reactome
COPII-mediated vesicle transport
Reactome
ER to Golgi Anterograde Transport
Name
Explore in Pharos
Explore in Source
Asparagine N-linked glycosylation
COPI-dependent Golgi-to-ER retrograde traffic
COPI-mediated anterograde transport
COPII-mediated vesicle transport
ER to Golgi Anterograde Transport
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
1
1
27.3
1
1
1
4.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
27.3
1
4.6
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
NSF attachment protein gamma
VGNC:7326
468475
Mouse
MGI:104561
108123
Rat
RGD:1310109
307382
Dog
NSF attachment protein gamma
VGNC:43622
608647
Horse
NSF attachment protein gamma
VGNC:20562
100050057
Species
Name
OMA
EggNOG
Inparanoid
Chimp
NSF attachment protein gamma
Mouse
Rat
Dog
NSF attachment protein gamma
Horse
NSF attachment protein gamma
Publication Statistics
PubMed Score 49.22
PubMed score by year
PubTator Score 35.75
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title