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Tbio
NAP1L5
Nucleosome assembly protein 1-like 5

Protein Summary
Description
This gene encodes a protein that shares sequence similarity to nucleosome assembly factors, but may be localized to the cytoplasm rather than the nucleus. Expression of this gene is downregulated in hepatocellular carcinomas. This gene is located within a differentially methylated region (DMR) and is imprinted and paternally expressed. There is a related pseudogene on chromosome 4. [provided by RefSeq, Nov 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000323061
  • ENSP00000320488
  • ENSG00000177432

Symbol
  • DRLM
  • DRLM
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.67
PubMedID
0.62
histone modification site profile
0.61
small molecule perturbation
0.61
gene perturbation
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.09   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.09   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (77)
TSPYL4
Tdark
Novelty:  0.4538252
p_int:  0.999994384
p_ni:  0.000005604
p_wrong:  1.3e-8
Score:  0.484
Data Source:  BioPlex,STRINGDB
SKA1
Tbio
Novelty:  0.01777146
p_int:  0.999920977
p_ni:  0.000078292
p_wrong:  7.31e-7
Score:  0.183
Data Source:  BioPlex,STRINGDB
ABT1
Tbio
Novelty:  0.05236553
p_int:  0.999594209
p_ni:  0.000405791
Score:  0.431
Data Source:  BioPlex,STRINGDB
PDCD2L
Tbio
Novelty:  0.33193498
p_int:  0.999559891
p_ni:  0.000440109
Score:  0.549
Data Source:  BioPlex,STRINGDB
RNF138
Tbio
Family:  TF
Novelty:  0.07543428
p_int:  0.999289733
p_ni:  0.000710267
Score:  0.203
Data Source:  BioPlex,STRINGDB
NOL6
Tbio
Novelty:  0.10002413
p_int:  0.99910631
p_ni:  0.000893686
p_wrong:  4e-9
Score:  0.798
Data Source:  BioPlex,STRINGDB
RRP7A
Tbio
Novelty:  0.11315285
p_int:  0.998975244
p_ni:  0.001024756
Score:  0.527
Data Source:  BioPlex,STRINGDB
IQGAP1
Tbio
Family:  Enzyme
Novelty:  0.00434481
p_int:  0.995052348
p_ni:  0.004947652
Data Source:  BioPlex
NAP1L1
Tbio
Novelty:  0.03895314
p_int:  0.992008587
p_ni:  0.007991413
Score:  0.351
Data Source:  BioPlex,STRINGDB
CCDC102A
Tdark
Novelty:  1.89784272
p_int:  0.990454011
p_ni:  0.009545989
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
9
13
26
98.4
waist-hip ratio
2
11
11
95.4
hip circumference
1
2
2
89.4
waist circumference
1
5
5
88.5
BMI-adjusted waist circumference
1
4
4
83.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
26
98.4
waist-hip ratio
11
95.4
hip circumference
2
89.4
waist circumference
5
88.5
BMI-adjusted waist circumference
4
83.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
nucleosome assembly protein 1 like 5
VGNC:13040
742154
Macaque
nucleosome assembly protein 1 like 5 [Source:HGNC Symbol;Acc:HGNC:19968]
Mouse
MGI:1923555
58243
Rat
RGD:1584123
688843
Dog
nucleosome assembly protein 1 like 5
VGNC:43618
607931
Species
Name
OMA
EggNOG
Inparanoid
Chimp
nucleosome assembly protein 1 like 5
Macaque
nucleosome assembly protein 1 like 5 [Source:HGNC Symbol;Acc:HGNC:19968]
Mouse
Rat
Dog
nucleosome assembly protein 1 like 5
Publication Statistics
PubMed Score 10.09
PubMed score by year
PubTator Score 3.16
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title