NANS
Sialic acid synthase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.99 | ||
disease perturbation | 0.98 | ||
virus perturbation | 0.83 | ||
protein domain | 0.73 | ||
transcription factor | 0.69 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Asparagine N-linked glycosylation | ||||
Reactome | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | Sialic acid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Asparagine N-linked glycosylation | ||||
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | ||||
Metabolism of proteins | ||||
Post-translational protein modification | ||||
Sialic acid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | Reactome | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 1 | 1 | 1 | 83.1 | |||||
red blood cell density measurement | 1 | 1 | 1 | 81.3 | |||||
eosinophil count | 2 | 1 | 2 | 52 | |||||
reticulocyte count | 1 | 1 | 1 | 50.6 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 50.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 1 | 83.1 | |||||
red blood cell density measurement | 1 | 81.3 | |||||
eosinophil count | 2 | 52 | |||||
reticulocyte count | 1 | 50.6 | |||||
mean reticulocyte volume | 1 | 50.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | N-acetylneuraminate synthase | VGNC:4796 | 743934 | |||||
Mouse | MGI:2149820 | 94181 | ||||||
Rat | RGD:1311943 | 298071 | ||||||
Dog | N-acetylneuraminate synthase | VGNC:43615 | 481624 | |||||
Horse | N-acetylneuraminate synthase | VGNC:20556 | 100064126 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | N-acetylneuraminate synthase | |||||
Mouse | ||||||
Rat | ||||||
Dog | N-acetylneuraminate synthase | |||||
Horse | N-acetylneuraminate synthase | |||||
PMID | Year | Title |
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