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Tbio
NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

Protein Summary
Description
Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361671
  • ENSP00000354972
  • ENSG00000135040
  • ENST00000376040
  • ENSP00000365208

Symbol
  • EGAP
  • MAK10
  • EGAP
  • MAK10
  • MAK10P
  • bA379P1.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.95
transcription factor perturbation
0.94
disease perturbation
0.9
kinase perturbation
0.66
transcription factor binding site profile
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.67   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 97   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.67   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 97   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0