Tdark MZT1 Mitotic-spindle organizing protein 1

Protein Summary

Description

Required for gamma-tubulin complex recruitment to the centrosome.

Uniprot Accession IDs

• Q08AG7
• Q5W0P5

Gene Name

• MZT1

Ensembl ID

• ENST00000377818
• ENSP00000367049
• ENSG00000204899

Symbol

• C13orf37
• MOZART1
• MOZART1
• C13orf37

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.9
transcription factor binding site profile	0.69
virus perturbation	0.68
cell type or tissue	0.66
kinase perturbation	0.66

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.76   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 27   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.76   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0