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Tdark
MYO1H
Unconventional myosin-Ih

Protein Summary
Description
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000431443
  • ENSP00000444076
  • ENSG00000174527
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.57
tissue sample
0.55
gene perturbation
0.53
cell type or tissue
0.47
microRNA
0.46


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.47   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.47   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
KIAA1210
Tdark
Novelty:  1.23692019
Score:  0.71
Data Source:  STRINGDB
ANKRD24
Tdark
Novelty:  1.1511349
Score:  0.653
Data Source:  STRINGDB
OR1J4
Tdark
Family:  oGPCR
Novelty:  3.07228916
Score:  0.634
Data Source:  STRINGDB
GIPC3
Tbio
Novelty:  0.14970604
Score:  0.633
Data Source:  STRINGDB
TBCK
Tbio
Family:  Kinase
Novelty:  0.08568145
Score:  0.604
Data Source:  STRINGDB
TXLNG
Tbio
Novelty:  0.08274423
Score:  0.571
Data Source:  STRINGDB
ARAP2
Tbio
Novelty:  0.04566051
Score:  0.567
Data Source:  STRINGDB
FRYL
Tdark
Novelty:  0.13893531
Score:  0.56
Data Source:  STRINGDB
MATN1
Tbio
Novelty:  0.00337153
Score:  0.557
Data Source:  STRINGDB
GRXCR1
Tdark
Novelty:  0.17455124
Score:  0.552
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (23)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
10
7
15
96.7
neuroticism measurement
5
8
4
7.3
85.1
2
2
1
1.2
79.4
diet measurement
3
3
4
72.8
red blood cell distribution width
2
2
2
72.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
15
96.7
neuroticism measurement
4
7.3
85.1
1
1.2
79.4
diet measurement
4
72.8
red blood cell distribution width
2
72.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
myosin IH
VGNC:13329
452221
Mouse
MGI:1914674
231646
Dog
myosin IH
VGNC:43566
100685393
Horse
myosin IH
VGNC:20505
100066688
Cow
myosin IH
VGNC:31823
525975
Species
Name
OMA
EggNOG
Inparanoid
Chimp
myosin IH
Mouse
Dog
myosin IH
Horse
myosin IH
Cow
myosin IH
Publication Statistics
PubMed Score 8.47
PubMed score by year
PubTator Score 3.54
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title