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Tbio
MYO1D
Unconventional myosin-Id

Protein Summary
Description
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000318217
  • ENSP00000324527
  • ENSG00000176658

Symbol
  • KIAA0727
  • myr4
  • PPP1R108
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.99
interacting protein
0.9
virus perturbation
0.9
transcription factor binding site profile
0.87
trait
0.86


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.41   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 96   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.41   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 96   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (52)
PEX19
Tbio
Novelty:  0.00605342
p_int:  0.997856865
p_ni:  0.002143135
Score:  0.169
Data Source:  BioPlex,STRINGDB
PSMC4
Tchem
Family:  Enzyme
Novelty:  0.01717597
p_int:  0.997515327
p_ni:  0.002484673
Data Source:  BioPlex
UBB
Tbio
Novelty:  0.00661254
p_int:  0.987212279
p_ni:  0.012787721
Score:  0.264
Data Source:  BioPlex,STRINGDB
DKK3
Tbio
Novelty:  0.00519275
p_int:  0.986229023
p_ni:  0.013770977
Score:  0.296
Data Source:  BioPlex,STRINGDB
FBXO40
Tbio
Novelty:  0.20308726
p_int:  0.975867731
p_ni:  0.024132269
Score:  0.189
Data Source:  BioPlex,STRINGDB
Q8NFQ8
Tbio
Novelty:  0.08912351
p_int:  0.957510621
p_ni:  0.042489379
Data Source:  BioPlex
TBC1D9B
Tdark
Novelty:  0.66719861
p_int:  0.952344016
p_ni:  0.047655984
Score:  0.279
Data Source:  BioPlex,STRINGDB
BTD
Tbio
Family:  Enzyme
Novelty:  0.01638573
p_int:  0.945770079
p_ni:  0.054229921
Score:  0.239
Data Source:  BioPlex,STRINGDB
HAVCR2
Tbio
Novelty:  0.00155885
p_int:  0.92701575
p_ni:  0.07298425
Data Source:  BioPlex
EID1
Tbio
Novelty:  0.02414732
p_int:  0.908910823
p_ni:  0.091089177
Score:  0.392
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (26)
Find Similar Targets
Items per page:
10
1 – 7 of 7
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
4
5
98.3
reticulocyte count
7
5
7
92.9
reticulocyte measurement
3
1
3
78.3
refractive error measurement
3
2
3
8.6
71.4
Myopia
2
2
0
4.8
69.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
5
98.3
reticulocyte count
7
92.9
reticulocyte measurement
3
78.3
refractive error measurement
3
8.6
71.4
Myopia
0
4.8
69.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
myosin ID
VGNC:12495
454576
Macaque
myosin ID
718097
Mouse
MGI:107728
338367
Rat
RGD:621321
25485
Dog
myosin ID
VGNC:43563
491153
Species
Name
OMA
EggNOG
Inparanoid
Chimp
myosin ID
Macaque
myosin ID
Mouse
Rat
Dog
myosin ID
Publication Statistics
PubMed Score 37.41
PubMed score by year
PubTator Score 12.26
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title