Tchem MYLK4 Myosin light chain kinase family member 4

Protein Summary

Uniprot Accession IDs

• Q86YV6
• A2RUC0
• Q5TAW2

Gene Name

• MYLK4

Ensembl ID

• ENST00000274643
• ENSP00000274643
• ENSG00000145949

Symbol

• SGK085
• SgK085

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.9
protein domain	0.85
gene perturbation	0.81
microRNA	0.79
tissue sample	0.55

Protein Classes

DTO Classes

Protein / Kinase / Protein Kinase / Camk Group / Mlck Family / Myosin Light Chain Kinase Family Member 4

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.31   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 119   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.31   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 1