MYLK4
Myosin light chain kinase family member 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.9 | ||
protein domain | 0.85 | ||
gene perturbation | 0.81 | ||
microRNA | 0.79 | ||
tissue sample | 0.55 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
KEGG | Platelet activation | ||||
KEGG | Focal adhesion | ||||
KEGG | Oxytocin signaling pathway | ||||
KEGG | Gastric acid secretion | ||||
KEGG | Regulation of actin cytoskeleton | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Platelet activation | ||||
Focal adhesion | ||||
Oxytocin signaling pathway | ||||
Gastric acid secretion | ||||
Regulation of actin cytoskeleton | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 2 | 3 | 52.7 | |||||
platelet crit | 1 | 1 | 1 | 50.6 | |||||
beta-amyloid 1-42 measurement | 1 | 1 | 1 | 21.5 | |||||
1 | 1 | 0 | 2.5 | 14.2 | |||||
disease recurrence | 1 | 1 | 0 | 2.5 | 14.2 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 52.7 | |||||
platelet crit | 1 | 50.6 | |||||
beta-amyloid 1-42 measurement | 1 | 21.5 | |||||
0 | 2.5 | 14.2 | |||||
disease recurrence | 0 | 2.5 | 14.2 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | myosin light chain kinase family member 4 | VGNC:3499 | 471840 | |||||
Macaque | myosin light chain kinase family member 4 | 707361 | ||||||
Mouse | MGI:3643758 | 238564 | ||||||
Dog | myosin light chain kinase family member 4 | 488190 | ||||||
Horse | myosin light chain kinase family member 4 [Source:HGNC Symbol;Acc:HGNC:27972] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | myosin light chain kinase family member 4 | |||||
Macaque | myosin light chain kinase family member 4 | |||||
Mouse | ||||||
Dog | myosin light chain kinase family member 4 | |||||
Horse | myosin light chain kinase family member 4 [Source:HGNC Symbol;Acc:HGNC:27972] | |||||
PMID | Year | Title |
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