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Tbio
MYH4
Myosin-4

Protein Summary
Description
Muscle contraction.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000255381
  • ENSP00000255381
  • ENSG00000264424

Symbol
  • MYH2B
  • MyHC-2B
  • MyHC-IIb
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.98
protein domain
0.85
cell type or tissue
0.7
gene perturbation
0.6
cellular component
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 146.31   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 146.31   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (133)
TLE3
Tbio
Novelty:  0.02641884
p_int:  0.999999997
p_ni:  2e-9
p_wrong:  2e-9
Score:  0.206
Data Source:  BioPlex,STRINGDB
ABTB2
Tdark
Novelty:  0.45729157
p_int:  0.99999999
p_ni:  9e-9
Data Source:  BioPlex
RSPH6A
Tdark
Novelty:  0.03734897
p_int:  0.999999988
p_ni:  1.2e-8
Data Source:  BioPlex
MECOM
Tbio
Family:  TF; Epigenetic
Novelty:  0.00500501
p_int:  0.999999958
p_ni:  4.2e-8
Data Source:  BioPlex
HIF1A
Tchem
Family:  TF
Novelty:  0.00011503
p_int:  0.999999711
p_ni:  2.88e-7
p_wrong:  1e-9
Score:  0.215
Data Source:  BioPlex,STRINGDB
LZTR1
Tbio
Novelty:  0.02363333
p_int:  0.999998116
p_ni:  0.000001884
Data Source:  BioPlex
TMEM260
Tdark
Novelty:  0.31409768
p_int:  0.999940316
p_ni:  0.000059684
Score:  0.239
Data Source:  BioPlex,STRINGDB
AURKC
Tchem
Family:  Kinase
Novelty:  0.00950433
p_int:  0.999937882
p_ni:  0.000062118
Score:  0.3
Data Source:  BioPlex,STRINGDB
SIX1
Tbio
Family:  TF
Novelty:  0.00415613
p_int:  0.999936308
p_ni:  0.000063682
p_wrong:  1e-8
Score:  0.469
Data Source:  BioPlex,STRINGDB
SYT3
Tbio
Novelty:  0.02593006
p_int:  0.999570661
p_ni:  0.000429338
p_wrong:  2e-9
Score:  0.188
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (14)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Non-traceable Author Statement (NAS)
BHF-UCL
Non-traceable Author Statement (NAS)
UniProtKB
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
myosin heavy chain 4
VGNC:12486
468396
Macaque
myosin heavy chain 4
717888
Mouse
MGI:1339713
17884
Dog
myosin heavy chain 4
479502
Cow
myosin, heavy chain 4, skeletal muscle
408020
Species
Name
OMA
EggNOG
Inparanoid
Chimp
myosin heavy chain 4
Macaque
myosin heavy chain 4
Mouse
Dog
myosin heavy chain 4
Cow
myosin, heavy chain 4, skeletal muscle
Publication Statistics
PubMed Score 146.31
PubMed score by year
PubTator Score 17.05
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title