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Tbio
MYCL
Protein L-Myc

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372815
  • ENSP00000361902
  • ENSG00000116990
  • ENST00000372816
  • ENSP00000361903
  • ENST00000397332
  • ENSP00000380494

Symbol
  • BHLHE38
  • LMYC
  • MYCL1
  • LMYC
  • L-Myc
  • MYCL1
  • bHLHe38
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.89
transcription factor binding site profile
0.78
microRNA
0.69
histone modification site profile
0.65
cell type or tissue
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 250.23   (req: < 5)
Gene RIFs: 17   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 250.23   (req: >= 5)
Gene RIFs: 17   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (77)
KLC3
Tbio
Novelty:  0.0528937
p_int:  0.99999996
p_ni:  1.1e-8
p_wrong:  2.9e-8
Score:  0.625
Data Source:  BioPlex,STRINGDB
KLC4
Tdark
Novelty:  0.32552746
p_int:  0.999999937
p_ni:  6.3e-8
Data Source:  BioPlex
KAT5
Tchem
Family:  Epigenetic
Novelty:  0.00368348
p_int:  0.999999658
p_ni:  3.41e-7
p_wrong:  1e-9
Score:  0.727
Data Source:  BioPlex,STRINGDB
EPC1
Tbio
Novelty:  0.03216371
p_int:  0.999999269
p_ni:  7.31e-7
Score:  0.72
Data Source:  BioPlex,STRINGDB
ING3
Tbio
Family:  Epigenetic
Novelty:  0.01696145
p_int:  0.999999259
p_ni:  7.41e-7
Score:  0.749
Data Source:  BioPlex,STRINGDB
EPC2
Tbio
Novelty:  0.02760809
p_int:  0.99999829
p_ni:  0.00000171
Score:  0.724
Data Source:  BioPlex,STRINGDB
EP400
Tbio
Novelty:  0.02013098
p_int:  0.999997088
p_ni:  0.000002912
Score:  0.785
Data Source:  BioPlex,STRINGDB
KIF5A
Tbio
Novelty:  0.01277095
p_int:  0.999996918
p_ni:  0.000003082
Data Source:  BioPlex
TRRAP
Tbio
Novelty:  0.01517245
p_int:  0.999996668
p_ni:  0.000003332
Score:  0.752
Data Source:  BioPlex,STRINGDB
KLC2
Tbio
Novelty:  0.06284367
p_int:  0.99999333
p_ni:  0.00000667
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
2
2
76.6
mean platelet volume
2
2
2
76.4
hemoglobin measurement
2
2
2
75.6
hematocrit
2
2
2
70.2
red blood cell distribution width
2
2
2
64.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
76.6
mean platelet volume
2
76.4
hemoglobin measurement
2
75.6
hematocrit
2
70.2
red blood cell distribution width
2
64.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
MYCL proto-oncogene, bHLH transcription factor
VGNC:14803
469291
Macaque
MYCL proto-oncogene, bHLH transcription factor
716497
Mouse
MGI:96799
16918
Rat
RGD:1588591
298506
Dog
MYCL proto-oncogene, bHLH transcription factor
VGNC:43529
482461
Species
Name
OMA
EggNOG
Inparanoid
Chimp
MYCL proto-oncogene, bHLH transcription factor
Macaque
MYCL proto-oncogene, bHLH transcription factor
Mouse
Rat
Dog
MYCL proto-oncogene, bHLH transcription factor
Publication Statistics
PubMed Score 250.23
PubMed score by year
PubTator Score 187.07
PubTator score by year
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Related Publications
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PMID
Year
Title