MYBPC3
Myosin-binding protein C, cardiac-type
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase | 0.85 | ||
protein domain | 0.85 | ||
cell type or tissue | 0.76 | ||
biological term | 0.74 | ||
gene perturbation | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Muscle contraction | ||||
Reactome | Striated Muscle Contraction | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Muscle contraction | ||||
Striated Muscle Contraction | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Mutant Phenotype (IMP) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Non-traceable Author Statement (NAS) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 11 | 21 | 31 | 99.6 | |||||
apolipoprotein A 1 measurement | 2 | 11 | 12 | 98.8 | |||||
IGF-1 measurement | 1 | 8 | 8 | 96.1 | |||||
triglyceride measurement | 4 | 8 | 8 | 96 | |||||
C-reactive protein measurement | 4 | 7 | 8 | 95.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 31 | 99.6 | |||||
apolipoprotein A 1 measurement | 12 | 98.8 | |||||
IGF-1 measurement | 8 | 96.1 | |||||
triglyceride measurement | 8 | 96 | |||||
C-reactive protein measurement | 8 | 95.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | myosin binding protein C, cardiac | 451168 | ||||||
Macaque | myosin binding protein C, cardiac | 712093 | ||||||
Mouse | MGI:102844 | 17868 | ||||||
Rat | RGD:1305950 | 295929 | ||||||
Dog | myosin binding protein C, cardiac | VGNC:43524 | 483624 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | myosin binding protein C, cardiac | |||||
Macaque | myosin binding protein C, cardiac | |||||
Mouse | ||||||
Rat | ||||||
Dog | myosin binding protein C, cardiac | |||||
PMID | Year | Title |
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