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Tbio
MYADM
Myeloid-associated differentiation marker

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000336967
  • ENSP00000337222
  • ENSG00000179820
  • ENST00000391768
  • ENSP00000375648
  • ENST00000391769
  • ENSP00000375649
  • ENST00000391770
  • ENSP00000375650
  • ENST00000391771
  • ENSP00000375651

Symbol
  • SB135
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
small molecule perturbation
0.92
biological process
0.9
transcription factor
0.8
cell type or tissue
0.64


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.58   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 174   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.58   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 174   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (55)
TGFBR2
Tchem
Family:  Kinase
Novelty:  0.00085381
p_int:  0.999418203
p_ni:  0.000580601
p_wrong:  0.000001196
Data Source:  BioPlex
NTRK3
Tclin
Family:  Kinase
Novelty:  0.00177321
p_int:  0.999286754
p_ni:  0.000704051
p_wrong:  0.000009195
Data Source:  BioPlex
PTGER3
Tclin
Family:  GPCR
Novelty:  0.0012681
p_int:  0.999124332
p_ni:  0.000873849
p_wrong:  0.000001819
Data Source:  BioPlex
TMEM200A
Tdark
Novelty:  0.25580793
p_int:  0.99901018
p_ni:  0.000988974
p_wrong:  8.46e-7
Data Source:  BioPlex
KIR2DL1
Tbio
Novelty:  0.00523657
p_int:  0.997316513
p_ni:  0.002574816
p_wrong:  0.000108671
Data Source:  BioPlex
TACR3
Tchem
Family:  GPCR
Novelty:  0.00351352
p_int:  0.996838854
p_ni:  0.00298683
p_wrong:  0.000174317
Data Source:  BioPlex
CD244
Tbio
Novelty:  0.01137579
p_int:  0.996323529
p_ni:  0.002661402
p_wrong:  0.001015069
Data Source:  BioPlex
MTUS2
Tbio
Novelty:  0.13504593
p_int:  0.996094178
p_ni:  0.00390581
p_wrong:  1.2e-8
Data Source:  BioPlex
CTLA4
Tclin
Novelty:  0.00012781
p_int:  0.995867454
p_ni:  0.004031097
p_wrong:  0.000101449
Data Source:  BioPlex
ARF6
Tbio
Family:  Enzyme
Novelty:  0.00278138
p_int:  0.995848568
p_ni:  0.004151327
p_wrong:  1.05e-7
Score:  0.557
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (16)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
interleukin 18 measurement
1
3
3
93.6
monocyte count
2
2
2
91.2
monocyte percentage of leukocytes
2
1
2
88
granulocyte percentage of myeloid white cells
1
1
1
85.5
caspase-8 measurement
1
1
1
85.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
interleukin 18 measurement
3
93.6
monocyte count
2
91.2
monocyte percentage of leukocytes
2
88
granulocyte percentage of myeloid white cells
1
85.5
caspase-8 measurement
1
85.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1355332
50918
Rat
RGD:727835
369016
Dog
myeloid-associated differentiation marker
100855913
Horse
myeloid associated differentiation marker
VGNC:20458
100062591
Cow
myeloid associated differentiation marker
506295
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
myeloid-associated differentiation marker
Horse
myeloid associated differentiation marker
Cow
myeloid associated differentiation marker
Publication Statistics
PubMed Score 11.58
PubMed score by year
PubTator Score 4.46
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title