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Tdark
MXRA7
Matrix-remodeling-associated protein 7

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355797
  • ENSP00000348050
  • ENSG00000182534
  • ENST00000375036
  • ENSP00000364176
  • ENST00000449428
  • ENSP00000391466
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
cell type or tissue
0.85
disease perturbation
0.74
small molecule perturbation
0.65
microRNA
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.94   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.94   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
GUCY1B1
Tclin
Family:  Enzyme
Novelty:  0.03618378
p_int:  1
Score:  0.282
Data Source:  BioPlex,STRINGDB
PCDHA12
Tdark
Novelty:  0.71618264
p_int:  0.98998349
p_ni:  0.003421922
p_wrong:  0.006594588
Score:  0.187
Data Source:  BioPlex,STRINGDB
METTL23
Tdark
Family:  Enzyme
Novelty:  0.22947963
Score:  0.801
Data Source:  STRINGDB
MXRA8
Tdark
Novelty:  0.00509012
Score:  0.737
Data Source:  STRINGDB
PRPSAP1
Tbio
Family:  Enzyme
Novelty:  0.08377292
Score:  0.699
Data Source:  STRINGDB
ST6GALNAC2
Tbio
Family:  Enzyme
Novelty:  0.03691665
Score:  0.679
Data Source:  STRINGDB
B4GALNT4
Tdark
Family:  Enzyme
Novelty:  0.19278471
Score:  0.673
Data Source:  STRINGDB
RHBDF2
Tbio
Family:  Enzyme
Novelty:  0.02487334
Score:  0.632
Data Source:  STRINGDB
C1QTNF4
Tbio
Novelty:  0.10701626
Score:  0.573
Data Source:  STRINGDB
PRPSAP2
Tbio
Family:  Enzyme
Novelty:  0.12017454
Score:  0.53
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
1
2
63.7
pulse pressure measurement
1
1
1
51.7
mathematical ability
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
63.7
pulse pressure measurement
1
51.7
mathematical ability
1
21.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1914872
67622
Rat
RGD:1594666
690599
Xenopus
matrix-remodelling associated 7
XB-GENE-953446
594877
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Xenopus
matrix-remodelling associated 7
Publication Statistics
PubMed Score 5.94
PubMed score by year
PubTator Score 1.70
PubTator score by year
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Related Publications
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PMID
Year
Title