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Tdark
MTMR10
Myotubularin-related protein 10

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000435680
  • ENSP00000402537
  • ENSG00000166912
  • ENST00000563714
  • ENSP00000457390
  • ENST00000568604
  • ENSP00000457903
  • ENST00000621195
  • ENSP00000484437
  • ENSG00000277086
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
phenotype
0.9
transcription factor perturbation
0.84
histone modification site profile
0.81
transcription factor binding site profile
0.67
microRNA
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.92   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 31   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.92   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 31   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (17)
MTMR2
Tbio
Family:  Enzyme
Novelty:  0.01403122
Score:  0.927
Data Source:  Reactome,STRINGDB
OTUD7A
Tbio
Novelty:  0.09531354
Score:  0.827
Data Source:  STRINGDB
FAN1
Tbio
Family:  Enzyme
Novelty:  0.05719629
Score:  0.804
Data Source:  STRINGDB
CHRNA7
Tchem
Family:  IC
Novelty:  0.00590784
Score:  0.764
Data Source:  STRINGDB
KLF13
Tbio
Family:  TF
Novelty:  0.02028352
Score:  0.75
Data Source:  STRINGDB
TRPM1
Tchem
Family:  IC
Novelty:  0.00822899
Score:  0.726
Data Source:  STRINGDB
ARHGAP11B
Tbio
Family:  Enzyme
Novelty:  0.0783727
Score:  0.722
Data Source:  STRINGDB
IFT80
Tbio
Novelty:  0.04862973
Score:  0.711
Data Source:  STRINGDB
CHRFAM7A
Tbio
Novelty:  0.02547993
Score:  0.693
Data Source:  STRINGDB
NIPA2
Tbio
Novelty:  0.05451663
Score:  0.659
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
Metabolism (R-HSA-1430728)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
PI Metabolism
Reactome
Phospholipid metabolism
Reactome
Synthesis of PIPs at the early endosome membrane
Name
Explore in Pharos
Explore in Source
Metabolism
Metabolism of lipids
PI Metabolism
Phospholipid metabolism
Synthesis of PIPs at the early endosome membrane
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Traceable Author Statement (TAS)
Reactome
Disease Associations ()
No disease associations found
GWAS Traits (4)
Items per page:
1 – 4 of 4
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at onset
1
1
0
6.4
72.9
1
1
0
6.4
72.9
age at onset
1
1
0
6.4
72.9
1
1
0
6.4
72.9
Items per page:
1 – 4 of 4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at onset
0
6.4
72.9
0
6.4
72.9
age at onset
0
6.4
72.9
0
6.4
72.9
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
myotubularin related protein 10
VGNC:13410
453283
Macaque
myotubularin related protein 10
713182
Mouse
MGI:2142292
233315
Rat
RGD:1305958
309255
Dog
myotubularin related protein 10
VGNC:43479
479016
Species
Name
OMA
EggNOG
Inparanoid
Chimp
myotubularin related protein 10
Macaque
myotubularin related protein 10
Mouse
Rat
Dog
myotubularin related protein 10
Publication Statistics
PubMed Score 2.92
PubMed score by year
PubTator Score 1.08
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title