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Tdark
MTFR1L
Mitochondrial fission regulator 1-like

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374300
  • ENSP00000363418
  • ENSG00000117640
  • ENST00000374301
  • ENSP00000363419
  • ENST00000374303
  • ENSP00000363421
  • ENST00000374307
  • ENSP00000363426
  • ENST00000466284
  • ENSP00000434751
  • ENST00000474295
  • ENSP00000435461

Symbol
  • FAM54B
  • FAM54B
  • MST116
  • MSTP116
  • HYST1888
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.95
histone modification site profile
0.83
tissue sample
0.66
transcription factor binding site profile
0.66
transcription factor
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.18   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 18   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.18   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
MRPL12
Tbio
Novelty:  0.10646542
p_int:  0.999997762
p_ni:  0.000002237
p_wrong:  1e-9
Data Source:  BioPlex
GHITM
Tbio
Novelty:  0.00360652
p_int:  0.999969125
p_ni:  0.000030874
Data Source:  BioPlex
PIP
Tbio
Novelty:  0.00208509
p_int:  0.999441311
p_ni:  0.000557991
p_wrong:  6.98e-7
Data Source:  BioPlex
PFDN4
Tbio
Novelty:  0.02133605
p_int:  0.994962897
p_ni:  0.003888035
p_wrong:  0.001149068
Data Source:  BioPlex
OLFM4
Tbio
Novelty:  0.01048505
p_int:  0.991353832
p_ni:  0.008644464
p_wrong:  0.000001705
Score:  0.169
Data Source:  BioPlex,STRINGDB
TACR3
Tchem
Family:  GPCR
Novelty:  0.00351352
p_int:  0.990734406
p_ni:  0.00868722
p_wrong:  0.000578375
Data Source:  BioPlex
C6orf141
Tdark
Novelty:  1.46022784
p_int:  0.986692329
p_ni:  0.011367221
p_wrong:  0.00194045
Data Source:  BioPlex
SKP2
Tbio
Family:  Enzyme
Novelty:  0.00182658
p_int:  0.972650387
p_ni:  0.025327964
p_wrong:  0.002021649
Data Source:  BioPlex
SDF4
Tbio
Novelty:  0.00105893
p_int:  0.967806277
p_ni:  0.0297321
p_wrong:  0.002461623
Data Source:  BioPlex
PRG2
Tbio
Novelty:  0.00548995
p_int:  0.961620483
p_ni:  0.038372104
p_wrong:  0.000007413
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
2
2
66.6
red blood cell density measurement
1
1
1
64.9
hematocrit
2
2
2
63.6
waist-hip ratio
1
1
1
48.5
BMI-adjusted waist-hip ratio
1
1
1
42.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
66.6
red blood cell density measurement
1
64.9
hematocrit
2
63.6
waist-hip ratio
1
48.5
BMI-adjusted waist-hip ratio
1
42.3
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
mitochondrial fission regulator 1 like
VGNC:8391
735630
Macaque
mitochondrial fission regulator 1 like
713213
Mouse
MGI:1924074
76824
Rat
RGD:1305453
298549
Dog
mitochondrial fission regulator 1 like
VGNC:43469
487365
Species
Name
OMA
EggNOG
Inparanoid
Chimp
mitochondrial fission regulator 1 like
Macaque
mitochondrial fission regulator 1 like
Mouse
Rat
Dog
mitochondrial fission regulator 1 like
Publication Statistics
PubMed Score 0.18
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title