Tbio MT4 Metallothionein-4

Protein Summary

Description

Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia.

Uniprot Accession IDs

• P47944
• Q14DA1
• MT-4

Gene Name

• MT4

Ensembl ID

• ENST00000219162
• ENSP00000219162
• ENSG00000102891

Symbol

• MT-4
• MTIV
• MT-IV

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
co-expressed gene	0.98
PubMedID	0.59
protein domain	0.58
cell type or tissue	0.57
tissue	0.56

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 107.68   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 24   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 107.68   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0