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Tdark
MT1HL1
Metallothionein 1H-like protein 1

Protein Summary
Description
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. This gene is a retrotransposed gene, compared to MT1H (GeneID:4496). This retrogene is transcribed. It retains a full-length CDS, and is assumed to be translated. Compared to the MT1H product, this protein product differs at three internal amino acids, two of which are at metal-binding sites. [provided by RefSeq, Mar 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000464121
  • ENSP00000476141
  • ENSG00000244020

Symbol
  • MT1P2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.82
protein domain
0.73
tissue
0.65
cell type or tissue
0.52
transcription factor perturbation
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.39   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.39   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
MTF1
Tbio
Family:  TF
Novelty:  0.01350821
Score:  0.901
Data Source:  STRINGDB
CAT
Tbio
Family:  Enzyme
Novelty:  0.00181888
Score:  0.708
Data Source:  STRINGDB
SLC30A1
Tbio
Family:  Transporter
Novelty:  0.00528427
Score:  0.706
Data Source:  STRINGDB
HPGDS
Tchem
Family:  Enzyme
Novelty:  0.00019629
Score:  0.63
Data Source:  STRINGDB
ATOX1
Tbio
Novelty:  0.00509938
Score:  0.624
Data Source:  STRINGDB
SLC30A3
Tbio
Family:  Transporter
Novelty:  0.00683607
Score:  0.604
Data Source:  STRINGDB
SLC30A10
Tbio
Family:  Transporter
Novelty:  0.00448153
Score:  0.603
Data Source:  STRINGDB
SOD1
Tchem
Family:  Enzyme
Novelty:  0.00039653
Score:  0.598
Data Source:  STRINGDB
SLC31A1
Tbio
Family:  Transporter
Novelty:  0.00658529
Score:  0.593
Data Source:  STRINGDB
SLC30A5
Tbio
Family:  Transporter
Novelty:  0.02432633
Score:  0.583
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.39
PubMed score by year
PubTator Score 0.37
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title