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Tbio
MSMB
Beta-microseminoprotein

Protein Summary
Description
The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000581478
  • ENSP00000462641
  • ENSG00000263639
  • ENST00000582163
  • ENSP00000463092

Symbol
  • PRSP
  • MSP
  • PSP
  • IGBF
  • MSPB
  • PN44
  • PRPS
  • HPC13
  • PSP57
  • PSP94
  • PSP-94
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.97
cell type or tissue
0.89
tissue
0.6
biological term
0.59
small molecule perturbation
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 493.17   (req: < 5)
Gene RIFs: 51   (req: <= 3)
Antibodies: 602   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 493.17   (req: >= 5)
Gene RIFs: 51   (req: > 3)
Antibodies: 602   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0