MRPL55
39S ribosomal protein L55, mitochondrial
Protein Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding two different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]
- ENST00000295008
- ENSP00000295008
- ENSG00000162910
- ENST00000336300
- ENSP00000337361
- ENST00000336520
- ENSP00000337342
- ENST00000348259
- ENSP00000338189
- ENST00000366733
- ENSP00000355694
- ENST00000366734
- ENSP00000355695
- ENST00000366735
- ENSP00000355696
- ENST00000366736
- ENSP00000355697
- ENST00000366738
- ENSP00000355699
- ENST00000366739
- ENSP00000355700
- ENST00000366740
- ENSP00000355701
- ENST00000366741
- ENSP00000355702
- ENST00000366742
- ENSP00000355703
- ENST00000366744
- ENSP00000355705
- ENST00000366746
- ENSP00000355707
- ENST00000366747
- ENSP00000355708
- ENST00000391867
- ENSP00000375740
- ENST00000430433
- ENSP00000403614
- L55nt
- MRP-L55
- AAVG5835
- PRO19675
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.9 | ||
transcription factor binding site profile | 0.72 | ||
cell line | 0.61 | ||
cellular component | 0.61 | ||
virus perturbation | 0.55 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.42 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 67 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.42 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 67 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0