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Tbio
MOG
Myelin-oligodendrocyte glycoprotein

Protein Summary
Description
Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. (Microbial infection) Acts as a receptor for rubella virus. The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000259891
  • ENSP00000259891
  • ENSG00000137345
  • ENST00000359539
  • ENSP00000352534
  • ENST00000376888
  • ENSP00000366085
  • ENSG00000204655
  • ENST00000376891
  • ENSP00000366088
  • ENST00000376894
  • ENSP00000366091
  • ENST00000376898
  • ENSP00000366095
  • ENST00000376917
  • ENSP00000366115
  • ENST00000383521
  • ENSP00000373013
  • ENSG00000237834
  • ENST00000383525
  • ENSP00000373017
  • ENST00000383630
  • ENSP00000373126
  • ENST00000383631
  • ENSP00000373127
  • ENST00000396701
  • ENSP00000379929
  • ENST00000396704
  • ENSP00000379932
  • ENST00000400669
  • ENSP00000383510
  • ENST00000400671
  • ENSP00000383512
  • ENST00000400688
  • ENSP00000383526
  • ENST00000400691
  • ENSP00000383528
  • ENST00000412760
  • ENSP00000404245
  • ENST00000414889
  • ENSP00000403380
  • ENSG00000234623
  • ENST00000415546
  • ENSP00000404149
  • ENSG00000234096
  • ENST00000417019
  • ENSP00000404537
  • ENST00000419274
  • ENSP00000411489
  • ENSG00000236561
  • ENST00000419309
  • ENSP00000395005
  • ENST00000420045
  • ENSP00000390682
  • ENST00000423895
  • ENSP00000390632
  • ENSG00000230885
  • ENST00000425145
  • ENSP00000397101
  • ENST00000426782
  • ENSP00000410699
  • ENST00000427289
  • ENSP00000414489
  • ENST00000428719
  • ENSP00000397723
  • ENST00000430264
  • ENSP00000403058
  • ENST00000430351
  • ENSP00000410268
  • ENST00000431798
  • ENSP00000410866
  • ENST00000432271
  • ENSP00000389221
  • ENST00000433500
  • ENSP00000413364
  • ENST00000434177
  • ENSP00000398197
  • ENST00000438803
  • ENSP00000414862
  • ENST00000439634
  • ENSP00000404957
  • ENST00000439884
  • ENSP00000398394
  • ENST00000440561
  • ENSP00000409534
  • ENST00000442244
  • ENSP00000391516
  • ENST00000442444
  • ENSP00000414146
  • ENST00000442629
  • ENSP00000399240
  • ENST00000444674
  • ENSP00000390469
  • ENST00000447285
  • ENSP00000401609
  • ENST00000448816
  • ENSP00000397837
  • ENST00000449096
  • ENSP00000391898
  • ENST00000452233
  • ENSP00000394873
  • ENST00000452744
  • ENSP00000389022
  • ENSG00000232641
  • ENST00000457090
  • ENSP00000415883
  • ENST00000457626
  • ENSP00000402139
  • ENST00000458179
  • ENSP00000413370
  • ENST00000490427
  • ENSP00000420350
  • ENST00000494692
  • ENSP00000417405
  • ENST00000547083
  • ENSP00000449213
  • ENST00000548017
  • ENSP00000448732
  • ENST00000550849
  • ENSP00000449683
  • ENST00000551175
  • ENSP00000448879
  • ENST00000551993
  • ENSP00000446871
  • ENST00000553111
  • ENSP00000447099

Symbol
  • BTN6
  • BTNL11
  • MOGIG2
  • NRCLP7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.88
cell type or tissue
0.74
microRNA
0.68
gene perturbation
0.67
biological term
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2960.84   (req: < 5)
Gene RIFs: 72   (req: <= 3)
Antibodies: 365   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2960.84   (req: >= 5)
Gene RIFs: 72   (req: > 3)
Antibodies: 365   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0