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Tbio
MOB4
MOB-like protein phocein

Protein Summary
Description
May play a role in membrane trafficking, specifically in membrane budding reactions. This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000233892
  • ENSP00000233892
  • ENSG00000115540
  • ENST00000323303
  • ENSP00000315702
  • ENST00000409360
  • ENSP00000387289
  • ENST00000448447
  • ENSP00000405354

Symbol
  • MOB3
  • MOBKL3
  • PHOCN
  • PREI3
  • 2C4D
  • MOB1
  • MOB3
  • PHOCN
  • PREI3
  • CGI-95
  • MOBKL3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.96
hub protein
0.92
transcription factor binding site profile
0.92
cell type or tissue
0.82
transcription factor perturbation
0.74


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.46   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 178   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.46   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 178   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0