MMADHC
Methylmalonic aciduria and homocystinuria type D protein, mitochondrial
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 1 | ||
disease perturbation | 0.9 | ||
pathway | 0.78 | ||
phenotype | 0.68 | ||
transcription factor binding site profile | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
Reactome | Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD | ||||
Reactome | Defects in cobalamin (B12) metabolism | ||||
Reactome | Defects in vitamin and cofactor metabolism | ||||
Reactome | Disease | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD | ||||
Defects in cobalamin (B12) metabolism | ||||
Defects in vitamin and cofactor metabolism | ||||
Disease | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | methylmalonic aciduria and homocystinuria, cblD type | VGNC:6369 | 459653 | |||||
Macaque | methylmalonic aciduria and homocystinuria, cblD type | 693783 | ||||||
Mouse | MGI:1923786 | 109129 | ||||||
Rat | RGD:1303272 | 362134 | ||||||
Dog | methylmalonic aciduria and homocystinuria, cblD type | 476145 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | methylmalonic aciduria and homocystinuria, cblD type | |||||
Macaque | methylmalonic aciduria and homocystinuria, cblD type | |||||
Mouse | ||||||
Rat | ||||||
Dog | methylmalonic aciduria and homocystinuria, cblD type | |||||
PMID | Year | Title |
---|