You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
MLXIP
MLX-interacting protein

Protein Summary
Description
Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319080
  • ENSP00000312834
  • ENSG00000175727
  • ENST00000377037
  • ENSP00000366236
  • ENST00000538698
  • ENSP00000440769
  • ENST00000625732
  • ENSP00000486569
  • ENSG00000281178
  • ENST00000628109
  • ENSP00000486016
  • ENST00000629738
  • ENSP00000487003

Symbol
  • BHLHE36
  • KIAA0867
  • MIR
  • MONDOA
  • MIR
  • MONDOA
  • bHLHe36
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.74
microRNA
0.7
disease perturbation
0.62
transcription factor perturbation
0.61
tissue sample
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.37   (req: < 5)
Gene RIFs: 20   (req: <= 3)
Antibodies: 136   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.37   (req: >= 5)
Gene RIFs: 20   (req: > 3)
Antibodies: 136   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0