Protein Summary
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity).
- ENST00000612535
- ENSP00000477504
- ENSG00000271605
- ENST00000615220
- ENSP00000480749
- ENST00000616498
- ENSP00000481318
- ENST00000619286
- ENSP00000482801
- C17orf60
- MCA32
- MCA32
- MCA-32
- C17orf60
- Allergin-1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.85 | ||
tissue | 0.83 | ||
cellular component | 0.62 | ||
tissue sample | 0.59 | ||
chemical | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 16.73 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 95 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 16.73 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 95 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (12)
RYK
Family: Kinase
Novelty: 0.00910227
p_int: 0.999200401
p_ni: 0.000174654
p_wrong: 0.000624945
Score: 0.188
Data Source: BioPlex,STRINGDB
PLAA
Family: Enzyme
Novelty: 0.01164687
p_int: 0.980192643
p_ni: 0.019807357
Score: 0.23
Data Source: BioPlex,STRINGDB
INPPL1
Family: Enzyme
Novelty: 0.00634126
p_int: 0.96909872
p_ni: 0.03090128
Score: 0.184
Data Source: BioPlex,STRINGDB
GBF1
Novelty: 0.10901631
p_int: 0.912125224
p_ni: 0.087874776
Score: 0.188
Data Source: BioPlex,STRINGDB
PTPRD
Family: Enzyme
Novelty: 0.01059407
p_int: 0.890595433
p_ni: 0.10902636
p_wrong: 0.000378208
Data Source: BioPlex
FHL2
Novelty: 0.00501273
p_int: 0.827765455
p_ni: 0.145519053
p_wrong: 0.026715492
Score: 0.181
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (4)
Components (2)
Processes (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Non-traceable Author Statement (NAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | GOC | |||
Disease Associations (null)
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 1 | 2 | 68.6 | |||||
sex hormone-binding globulin measurement | 2 | 2 | 2 | 49.2 | |||||
cardiac troponin I measurement | 1 | 1 | 1 | 48.5 | |||||
vital capacity | 1 | 1 | 1 | 31.4 | |||||
1 | 1 | 0 | 1 | 24.5 | |||||
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 68.6 | |||||
sex hormone-binding globulin measurement | 2 | 49.2 | |||||
cardiac troponin I measurement | 1 | 48.5 | |||||
vital capacity | 1 | 31.4 | |||||
0 | 1 | 24.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (2)
1 – 2 of 2
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Dog | mast cell immunoglobulin like receptor 1 | VGNC:43235 | 480473 | |||||
Cow | mast cell immunoglobulin like receptor 1 | VGNC:31476 | 789682 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Dog | mast cell immunoglobulin like receptor 1 | |||||
Cow | mast cell immunoglobulin like receptor 1 | |||||
Publication Statistics
PubMed Score 16.73
PubMed score by year
PubTator Score 4.43
PubTator score by year
Related Publications
Text Mined References (5)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
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