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Tbio
MID1IP1
Mid1-interacting protein 1

Protein Summary
Description
Plays a role in the regulation of lipogenesis in liver. Up-regulates ACACA enzyme activity. Required for efficient lipid biosynthesis, including triacylglycerol, diacylglycerol and phospholipid. Involved in stabilization of microtubules (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000336949
  • ENSP00000338706
  • ENSG00000165175
  • ENST00000378474
  • ENSP00000367735
  • ENST00000457894
  • ENSP00000416670
  • ENST00000614558
  • ENSP00000483547

Symbol
  • MIG12
  • S14R
  • MIG12
  • THRSPL
  • G12-like
  • STRAIT11499
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.99
drug perturbation
0.96
disease perturbation
0.95
kinase perturbation
0.84
PubMedID
0.79


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.48   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 144   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.48   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 144   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (55)
KLHL25
Tbio
Novelty:  0.14475787
p_int:  0.999999985
p_ni:  1.4e-8
p_wrong:  1e-9
Data Source:  BioPlex
THRSP
Tbio
Novelty:  0.00938864
p_int:  0.99999905
p_ni:  9.5e-7
Score:  0.934
Data Source:  BioPlex,Reactome,STRINGDB
SUFU
Tbio
Novelty:  0.00475249
p_int:  0.999997786
p_ni:  0.000002214
Data Source:  BioPlex
SPATA2
Tbio
Novelty:  0.10553772
p_int:  0.999997135
p_ni:  0.000002849
p_wrong:  1.6e-8
Data Source:  BioPlex
DPH2
Tbio
Novelty:  0.04268301
p_int:  0.999980086
p_ni:  0.000019913
Data Source:  BioPlex
PRKAA1
Tclin
Family:  Kinase
Novelty:  0.01205826
p_int:  0.999959821
p_ni:  0.000040179
Data Source:  BioPlex
ELL
Tbio
Family:  Enzyme
Novelty:  0.00424352
p_int:  0.999948897
p_ni:  0.000051101
p_wrong:  1e-9
Data Source:  BioPlex
CYLD
Tbio
Family:  Enzyme
Novelty:  0.00215465
p_int:  0.99994539
p_ni:  0.00000341
p_wrong:  0.000051199
Data Source:  BioPlex
ACACA
Tchem
Family:  Enzyme
Novelty:  0.00248313
p_int:  0.999904045
p_ni:  0.000095955
Score:  0.492
Data Source:  BioPlex,STRINGDB
SAPCD2
Tbio
Novelty:  0.06798955
p_int:  0.999901502
p_ni:  0.000098493
p_wrong:  5e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Fatty acid metabolism (R-HSA-8978868)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Fatty acid metabolism
Reactome
Import of palmitoyl-CoA into the mitochondrial matrix
Reactome
Metabolism
Reactome
Metabolism of lipids
Name
Explore in Pharos
Explore in Source
Fatty acid metabolism
Import of palmitoyl-CoA into the mitochondrial matrix
Metabolism
Metabolism of lipids
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
MID1 interacting protein 1
698138
Mouse
MGI:1915291
68041
Rat
RGD:1303258
404280
Dog
MID1 interacting protein 1
VGNC:43223
491830
Horse
MID1 interacting protein 1
VGNC:20176
100055994
Species
Name
OMA
EggNOG
Inparanoid
Macaque
MID1 interacting protein 1
Mouse
Rat
Dog
MID1 interacting protein 1
Horse
MID1 interacting protein 1
Publication Statistics
PubMed Score 11.48
PubMed score by year
PubTator Score 2.72
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title