Tdark MFSD5 Molybdate-anion transporter

Protein Summary

Description

Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.

Uniprot Accession IDs

• Q6N075
• G3V1N7
• Q6NW04
• Q8N7W8
• Q8NCK0
• Q96IA5

Gene Name

• MFSD5

Ensembl ID

• ENST00000329548
• ENSP00000332624
• ENSG00000182544
• ENST00000534842
• ENSP00000442688

Symbol

• hsMOT2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.93
kinase perturbation	0.84
transcription factor binding site profile	0.68
transcription factor	0.64
tissue sample	0.59

Protein Classes

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc61 Molybdate Transporter Family / Molybdate-anion Transporter

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.73   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 86   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.73   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0