You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
MFSD11
UNC93-like protein MFSD11

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000336509
  • ENSP00000337240
  • ENSG00000092931
  • ENST00000355954
  • ENSP00000348225
  • ENST00000586622
  • ENSP00000466613
  • ENST00000588460
  • ENSP00000464932
  • ENST00000590514
  • ENSP00000468309
  • ENST00000593181
  • ENSP00000466782
  • ENST00000621483
  • ENSP00000485005

Symbol
  • ET
  • ET
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
transcription factor binding site profile
0.91
transcription factor
0.85
small molecule perturbation
0.72
histone modification site profile
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.76   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 47   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.76   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 47   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (5)
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (50)
SMAP2
Tbio
Novelty:  0.70006863
p_int:  0.997730333
p_ni:  0.002062794
p_wrong:  0.000206872
Score:  0.199
Data Source:  BioPlex,STRINGDB
UBE2Q1
Tbio
Novelty:  0.06489765
p_int:  0.996055704
p_ni:  0.003944172
p_wrong:  1.25e-7
Score:  0.325
Data Source:  BioPlex,STRINGDB
TUBB1
Tclin
Novelty:  0.02806117
p_int:  0.978382465
p_ni:  0.021617531
p_wrong:  5e-9
Score:  0.163
Data Source:  BioPlex,STRINGDB
MFSD5
Tdark
Novelty:  0.58146966
Score:  0.873
Data Source:  STRINGDB
SVOPL
Tdark
Novelty:  0.46448049
Score:  0.816
Data Source:  STRINGDB
SVOP
Tbio
Novelty:  0.0830639
Score:  0.811
Data Source:  STRINGDB
MFSD4B
Tdark
Novelty:  0.03380333
Score:  0.78
Data Source:  STRINGDB
MFSD10
Tbio
Novelty:  0.12830664
Score:  0.77
Data Source:  STRINGDB
SV2C
Tbio
Novelty:  0.03221681
Score:  0.766
Data Source:  STRINGDB
MFSD8
Tbio
Novelty:  0.03388459
Score:  0.755
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
corneal resistance factor
1
3
3
87.6
blood protein measurement
1
1
1
75
pulse pressure measurement
2
2
2
71.3
neutrophil count
3
1
3
53.6
educational attainment
1
2
2
42.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
corneal resistance factor
3
87.6
blood protein measurement
1
75
pulse pressure measurement
2
71.3
neutrophil count
3
53.6
educational attainment
2
42.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
major facilitator superfamily domain containing 11
VGNC:9377
100614093
Macaque
major facilitator superfamily domain containing 11
707770
Mouse
MGI:1917150
69900
Rat
RGD:1307394
360667
Dog
major facilitator superfamily domain containing 11
VGNC:43197
100856081
Species
Name
OMA
EggNOG
Inparanoid
Chimp
major facilitator superfamily domain containing 11
Macaque
major facilitator superfamily domain containing 11
Mouse
Rat
Dog
major facilitator superfamily domain containing 11
Publication Statistics
PubMed Score 24.76
PubMed score by year
PubTator Score 0.06
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title