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Tdark
METTL9
Methyltransferase-like protein 9

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358154
  • ENSP00000350874
  • ENSG00000197006
  • ENST00000396014
  • ENSP00000379335
  • ENST00000638803
  • ENSP00000491526
  • ENSG00000284548
  • ENST00000640479
  • ENSP00000491241

Symbol
  • DREV
  • DREV
  • PAP1
  • DREV1
  • CGI-81
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.9
disease perturbation
0.9
kinase perturbation
0.88
transcription factor perturbation
0.88
transcription factor binding site profile
0.85


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.25   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.25   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (57)
SLC39A5
Tbio
Family:  Transporter
Novelty:  0.05205571
p_int:  0.999877099
p_ni:  0.000122901
Data Source:  BioPlex
SLC30A1
Tbio
Family:  Transporter
Novelty:  0.00528427
p_int:  0.999342556
p_ni:  0.000657432
p_wrong:  1.1e-8
Data Source:  BioPlex
FUNDC2
Tbio
Novelty:  0.09695817
p_int:  0.998949275
p_ni:  0.000857955
p_wrong:  0.00019277
Data Source:  BioPlex
VMA21
Tdark
Family:  Enzyme
Novelty:  0.46129032
p_int:  0.998438022
p_ni:  0.001547967
p_wrong:  0.000014011
Data Source:  BioPlex
FUNDC1
Tbio
Novelty:  0.02333176
p_int:  0.998068977
p_ni:  0.000002112
p_wrong:  0.00192891
Data Source:  BioPlex
SLC30A6
Tbio
Family:  Transporter
Novelty:  0.06083299
p_int:  0.996103748
p_ni:  0.003893376
p_wrong:  0.000002876
Data Source:  BioPlex
PITHD1
Tdark
Novelty:  0.32046117
p_int:  0.99263836
p_ni:  0.007360659
p_wrong:  9.81e-7
Data Source:  BioPlex
LNPK
Tbio
Novelty:  0.07736762
p_int:  0.99223665
p_ni:  0.007763328
p_wrong:  2.2e-8
Data Source:  BioPlex
ACE
Tclin
Family:  Enzyme
Novelty:  0.00001993
p_int:  0.988621254
p_ni:  2.63e-7
p_wrong:  0.011378484
Data Source:  BioPlex
SLC30A5
Tbio
Family:  Transporter
Novelty:  0.02432633
p_int:  0.98110448
p_ni:  0.015305009
p_wrong:  0.003590511
Score:  0.159
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (8)
Items per page:
1 – 5 of 8
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
2
0
1
88
2
2
0
1
88
balding measurement
1
1
1
76.5
balding measurement
1
1
1
76.5
inflammatory biomarker measurement
1
1
0
53.4
39.6
Items per page:
1 – 5 of 8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1
88
0
1
88
balding measurement
1
76.5
balding measurement
1
76.5
inflammatory biomarker measurement
0
53.4
39.6
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
methyltransferase like 9
VGNC:5836
453982
Macaque
methyltransferase like 9
698159
Mouse
MGI:1914862
59052
Rat
RGD:2311609
100302453
Dog
methyltransferase like 9
VGNC:43183
479809
Species
Name
OMA
EggNOG
Inparanoid
Chimp
methyltransferase like 9
Macaque
methyltransferase like 9
Mouse
Rat
Dog
methyltransferase like 9
Publication Statistics
PubMed Score 7.25
PubMed score by year
PubTator Score 3.17
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title